The Antioxidant Effect of Morus alba Leaves Extract on Kidney, Testes, Spleen and Intestine of Mice

The current study aims at determining the antioxidant properties of Morus alba leaves extract (MLE) on various organs of mice. Forty male Swiss albino mice were divided into control group and three different groups which received three different doses of MLE orally for 10 days. The glutathione, nitrite/nitrate, malondialdehyde levels were estimated in kidney, testis, spleen and jejunum of adult male albino mice. Also, the levels of urea, creatinine and uric acid were determined in blood plasma of mice. The oral gavage of M. alba leaves extract induced a highly significant increment in glutathione level while it caused a highly significant reduction of nitrite/nitrate and malondialdehyde in all studied organs. In addition, blood urea nitrogen, creatinine and uric acid were improved. We speculated that, MLE scavenged the free radicals in different mice organs under investigation due to its antioxidant activity.